Intrauterine Insemination (IUI)

IUI (Intrauterine insemination) is offered by our center. IUI bypasses the cervix and places the sperm directly at the top of the uterus. From there sperm can reach the egg in the fallopian tubes within seconds.

Clomid or FSH. IUI is often effective in treating mild male factor infertility since sperm are concentrated prior to placing them in the uterus. IUI is also effective in treating cervical factor infertility because the sperm are inserted through the cervix using a catheter thus avoiding poor mucus and/or antibodies against sperm.

When a woman does not take any fertility medications in her IUI cycle, we refer to it as natural cycle insemination. Ovulation is timed by the patient, using ovulation predictor kits that test the urine. We can assist by ultrasound examinations. The couple arrives at our office on the day of the insemination and the husband provides the sperm. If preferable, sperm can be collected at home in a special sterile container. Sperm washing is subsequently done at our lab, which prepares a concentrated specimen to be placed into the uterus using a small catheter.

“Unprepared sperm” should never be placed directly into the uterus as severe adverse reactions may result. In IUI, the washed sperm specimen is aspirated into a small catheter and injected into the uterus through a painless procedure.

The IUI procedure is the same when women use either Clomid or injectable fertility medications (FSH), only that in these treatment cycles, they will be monitored more closely and the timing of ovulation may be controlled with medications. IUI in this situation carries the risk of multiple births since the number of eggs cannot be fully controlled. This means that there is a potential for high order (greater than two) multiple births. In order to manage the risk of multiple births, these IUI cycles must be monitored closely by a reproductive endocrinologist,infertility specialist to help optimally reduce the risk. Frequent dosage adjustments based upon each patient’s individual response may be required.